Endocrine Abstracts

Steroid-associated adverse events (SAAE) include hypertension, hyperglycemia, and diabetes, overweight and obesity and short stature.Aim: The goal of this study was to assess the occurrence of steroid-associated metabolic and clinical adverse events (SAAE) in patients with NS and frequent relapses treated with long-term prednisone compared to another high-risk group (obese children BMISDS > 2)Methods: Data of 30 children with S...

Although widely prescribed for their anti-inflammatory and immunosuppressive properties, glucocorticoids have various common metabolic side effects including hypertension, dysglycemia and diabetes. Aim: This study was carried out to investigate the prevalence of different metabolic components and dysglycemia in children with steroid sensitive nephrotic syndrome (SSNS) with multiple relapses for 5 years in relation to the cumulative dose of steroids.<...

Introduction: Long term prednisone therapy (LTPT) can be associated with overweight, obesity, and short stature. Both LTPT and obesity are considered risk factor for the occurrence of the different components of the metabolic syndrome (MetS).Aim: We studied steroid-associated metabolic and clinical adverse events in children with NS and frequent relapses treated with LTPT (obese vs non-obese). Methods: Data of 30 children with SSNS...

Nephrotic syndrome (NS) in children usually has an onset between 2-8 years of age and steroids form the mainstay of management. Therapy may affect growth in children with relapsing NS.Aim: This study was carried out to investigate linear growth and weigh gain in children with NS and multiple relapses who receiving long-term prednisone therapy (LTPT) for 5 years.Methods: Data of 30 children with SSNS was analysed retrospectively. Th...